Transplantation can be indicated in cases of irreversible organ failure, when conservative treatments are exhausted or not available. The solid organs that can be currently transplanted in children are: kidney, liver, heart, intestine and lung. Apart from solid organs, bone marrow and other tissues can also be transplanted: heart valves, skin, bone, etc.
In spite of the need of organ replacement, transplantation might be contraindicated in a minority of children with oncological diseases, sepsis or critical state. Every case requires individual evaluation.